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According to the Karolinska Institutes timeline of the Macchiarini case, the institute recruited Macchiarini as a visiting professor of regenerative medicine/stem cell biology in 2010, and the associated Karolinska University Hospital gave him a part-time contract as a consultant and surgeon around the same time. Award-winning documentary-maker Benita Alexander was swept off her feet by renowned Italian doctor Paolo Macchiarini in 2013 while she was working on a story about his pioneering medical work. She visits Mount Sinai weekly for blood work. Its actually meaningless for him, Gerdin says. In Macchiarinis case, the hope was that patients could be treated with stem cells taken from their own bone marrow. Macchiarini gave his regenerating windpipes to 17 or more patients worldwide. To some extent, they believed Macchiarini because he told them what they wanted to hear. Anyone can read what you share. Emanuela Pecchia: Everything We Know On Paolo Macchiarini Wife Ms. Seins trachea before, left, and her new transplanted trachea. Brazil Your tax-deductible contribution plays a critical role in sustaining this effort. COVID-19 About 11 centimeters (4 inches) long, one side curves like a halfpipe, composed of cartilage rings and ligaments. George Floyd Benita Alexander wearing a wig as she tracked down Paolo in Barcelona [Investigation Discovery]. And Murphy found that Macchiarinis claims about the wedding were almost all untrue and that the surgeon was married and had been for nearly 30 years. They didnt. The 18-hour procedure, conceived and led by Dr. Eric M. Genden Sr., chairman of otolaryngology-head and neck surgery at Mount Sinai Health System in New York, is a milestone because unlike kidneys, hearts and lungs the trachea has defied decades of transplantation attempts. Then, in October of 2009, another woman, who had been operated on by Paolo twice before, received her airway transplant. By this year, Dr. Genden said, her condition had deteriorated so that if we delay further, its not going to work out.. We were doing good research, but it didnt matter I thought I was going to lose my lab, my staff everything.. None other than Pope Francis would officiate, and his papal palace in Castel Gandolfo would serve as the venue. The Macchiarini scandal claimed many of his powerful friends. Also, in such a highly competitive environment, people are keen to show allegiance to their superiors and wary of criticising them. The apparent success of Ms. Seins operation is also notable because the trachea field has been rocked for years by a sensational scandal. The first was a Vanity Fair article about his affair with Benita Alexander, an award-winning producer for NBC News. Keep up with your favorite shows delivered to your inbox! The tube was necessary because her trachea the airway leading to the lungs had become damaged after she spent weeks on a ventilator for a severe asthma attack in 2014. In 2016, Vanity Fair published an expose on Paolo that uncovered even more damning evidence. Paolo Macchiarini at a press conference in 2008. US Capitol Benita Alexander with one of the custom-made gowns intended for her wedding [Investigation Discovery]. She says she feels she has been given a chance of being alive one more time.. Tennessee Macchiarini is known for his research fraud and manipulative behavior. In January 2016, Macchiarini received an extraordinary double dose of bad press. The media began calling him "Dr. Frankenstein" and said that he committed "the world's biggest medical fraud.". Disgraced tracheal transplant surgeon is handed North Carolina Ive never in my experience witnessed a fraud like this, with this level of international flair, Murphy told Vanity Fair. We now know that wasnt true. But they found prosecutors didnt prove Macchiarini was indifferent to the injuries or suffering that the surgeries might cause, the standard required for aggravated assault. The next morning, with the donor and Ms. Sein in adjacent rooms, a team of over 50 medical personnel assembled. Benita Alexander and Paolo Macchiarini in Venice, Italy [Investigation Discovery]. The maximum prison sentence for causing bodily harm is 4 years. He understood how difficult her life had become. Karolinskas leadership expected big things from their superstar, things that would bring prestige and funding to the institute. The operation, performed at one of the worlds most prestigious medical universities, part of the Karolinska Institute in Stockholm, was hailed as revolutionary. Disgraced Italian surgeon convicted of criminal harm to stem cell patient. Only four months after Macchiarini operated on Claudia Castillo, his results provisional but very positive were published online by the Lancet. Only three are still alive as of September 2020. However, Swedish TV reporters also decided to take a close look at Macchiarinis work. Paolo grew close to Alexander's daughter [Investigation Discovery], He was incredibly charming, worldly smart, sophisticated, and seemed very gentle," Benita told CrimeFeed. The plastic trachea that Yesim Cetir received disfigured her and made her last three years in life basically like torture, said Bosse Lindquist, a documentarian who broke the story in Sweden about Dr. Macchiarini in a television series, The Experiment.. Dr. Delaere developed another innovative method, performed on nine patients so far: implanting a section of donor trachea in a patients forearm for weeks until it develops blood vessels and can replace part of the patients trachea. He says prosecutors should have pressed for manslaughter charges because Macchiarini had no evidence that the tracheas he implanted would develop into normally functioning organs. Gerdin says the conviction on one count still shows that health care doesnt stand above the law. None have been forced to hold full and independent inquiries. She told CrimeFeed that, looking back, it seemed odd to her she had not met many of Paolo's close friends in Barcelona. Some of them have been successful, but theyre cumbersome in different ways and theyre not a trachea, Dr. Patterson said. In his case, his stem cells were seeded into the airway just hours before it was implanted into him, making it work perfectly fine. On May 13, Alexander left her job. It must be lined with cilia, hairlike projections like shag carpeting that move and clean the air we breathe in, he said. But after Alexander learned that Pope Francis was scheduled to visit South America at the time of their wedding, she confronted Macchiarini about his claims. Claudia Castillo with Dr Paolo Macchiarini. For the respect of privacy, his wifes identity is not revealed on the internet. Chatri Sityodtong Colleagues accused him of manipulating his results, even warning of the harm caused by these so-called regenerative windpipes. He was one of the best con-men I have ever come across, he added. As it was built from Claudias own cells, she didnt need to be on any risky immunosuppressant drugs. And then there are the surgeons on Dr. Death. The answer came only a couple of weeks later, when Swedish television began broadcasting a three-part expos of Macchiarini and his work. A High-Flying Italian Surgeons Fall From Grace, https://www.nytimes.com/2022/06/17/world/europe/macchiarini-windpipe-surgeon-deaths.html. Seven of the eight patients Paolo inserted tracheas into have died. How did the GameStop stock spike on Wall Street happen? Guided by a high-powered microscope, he used surgical thread half the diameter of a human hair. At first, they just connected as friends. Delaeres damning criticisms appeared in major medical journals, including the Lancet, but werent taken seriously by Karolinskas leadership. While there isnt enough data to actually prove this, we do have some key indicators. But when Dr. Sander S. Florman, director of Mount Sinais Transplantation Institute, and LiveOnNY, a nonprofit organ donation organization, agreed to collaborate, his wife, Audrey, encouraged him. The law is supposed to protect individuals from all types of assault, especially when they are powerless, said Dr. Bengt Gerdin, an independent investigator who was hired by the Karolinska Institute in 2015 to look into Dr. Macchiarinis work. Her global quest to find out the truth about the man who left her personal and professional life in shambles is documented in He Lied About Everything on Investigation Discovery. She considered backing out. Almost overnight, he became a superstar. And investigations by both institute and the hospital found coverups regarding Macchiarinis work. Macchiarinis fall was swift, but troubling questions remain about why he was allowed to continue his experiments for so long. Paolo, a visiting researcher at the prestigious Karolinska Institutet in Sweden, had shot to fame as the only doctor in the world who was able to use biological and synthetic scaffolds bathed in the patients' own stem cells for trachea transplants. On the contrary, they seemed to do more harm than good something that Macchiarini had for years concealed or downplayed in his scientific articles, press releases and interviews. On Friday Mr. Hurtig declined to comment on Paolos private affairs.. Reports of their success always seemed like hot air to him. Previously considered a pioneer for using both biological and synthetic scaffolds She had already spent $10,000 on engraved invitations made for a guest list that included the Obamas, the Clintons, Vladimir Putin, and Elton John. Thailand In 2013, the hospital halted future operations with synthetic trachea and opted to not extend Macchiarinis contract. How a star surgeon's personal and professional lives converged There he reinvented his technique. For their efforts, the whistleblowers were punished. They exchange their vows in Italy. A genius is a revolutionary by definition, a risk-taker and a law-breaker. Alexander said that Macchiarini told her he was still married to his wife because they were Catholic but were separated. Death for Season 2 at Peacock, From 'Truth About Pam' to 'Candy,' True-Crime EPs Tell the Truth (VIDEO). Investigations by the hospital and the Karolinska Institute revealed that issues with Dr. Macchiarinis work had been covered up. Starting in 2011, Macchiarini performed three transplantations of synthetic tracheas at Karolinska University Hospital, but one of those patients died in 2012, the timeline reports. Benita Alexander Before their wedding, the In Sweden, both the defense and the prosecution can appeal rulings, and senior prosecutor Karin Lundstrm-Kron says she and her colleagues will decide in the coming weeks. In other countries, more of Macchiarinis patients died after receiving one of his artificial windpipes. We have estimated Paolo Macchiarini's net worth , money, salary, income, and assets. They recently published an article in the New England Journal of Medicine admitting that stem cell research has mostly failed to live up to its therapeutic promise. At the time, Macchiarini was employed by the prestigious Karolinska Institute in Sweden. He traveled to Illinois to operate on a Korean toddler who was born without a trachea and who was going to be the youngest person to ever receive an artificial one. Any replacement trachea must be rigid or itll collapse like a straw in a McDonalds milkshake, Dr. Genden said. She would later discover that the woman in Barcelona had been living with Paolo for years, but that there were several other women in his life as well. They didnt even seek the approval of Stockholms ethical review board, which is based at Karolinska. But some of Alexander's friends began to become suspicious. In early 2014, four Karolinska doctors defied the reigning culture of silence by complaining about Macchiarini. But for now, lets focus solely on his medical patients, shall we? Paolo Macchiarinis most notable patient is Claudia Castillo. Born in 1977, this Colombian living in Spain woman suffered from tuberculosis-damaged airways. Some answers have emerged from the official inquiries into the Karolinska Institute and the Karolinska University hospital. It is unclear whether Dr. Macchiarini is still practicing medicine, but his lawyer said in May that he had no income. KI officials let him do this. Border crisis: Whats happening at the US-Mexico border? The court said the penalty was a suspended sentence, but did not specify how long the sentence would be if imposed. Who Were Paolo Macchiarinis Victims? - The Cinemaholic He did this by chemically stripping away the cells of a windpipe taken from a deceased donor; he then seeded the bare scaffold with stem cells taken from Castillos own bone marrow. First Successful Trachea Transplant a Medical Milestone - The A 29-year old woman from New Brunswick, New Jersey, posed as a high school student and attended classes for four days before she was caught and arrested. However, behind closed doors, Dr. Macchiarini was hiding a secret the procedures were not working. Surgeon Paolo Macchiarini was hailed for turning the dream of regenerative medicine into a reality until he was exposed as a con artist and false prophet. Likewise the whole idea of a wedding: Macchiarini was still married to his wife of 30 years. Her colleague had sent an article that said the pope would not be in Rome, or even Italy, on the day of their wedding. But as the big day approached, Alexander saw these plans unravel, and finally realised that her lover had lied about almost everything. But the vice-chancellor of Karolinska Institute, Anders Hamsten, wasnt bound by this judgement. Chief judge Bjoern Skaensberg said the court agreed that Macchiarinis operations were not consistent with science and proven experience, but the court determined that two of the interventions were justifiable.. Those few patients who are still alive including Castillo have survived in spite of the artificial windpipes they received. Change), You are commenting using your Facebook account. Indonesia So, how much is Paolo Macchiarini worth at the age of 64 years old? So far he has not been prosecuted in any of those countries. Michigan However, he eventually found out about his previous associations. Ohio Over the years, this possibility has generated great excitement and a huge amount of research. Next month, she will turn 57. He hopes the immunosuppressant drugs, which can create health risks, can be reduced or even stopped if the entire graft becomes filled with Sonias cells.. He said yeah, so I said Lets go for it., After extracting the donors organs, you go next door and you open up Sonia and you remove the diseased trachea, and there is no going back, Dr. Genden said. Team Lakay As Grinnemo recalls, it nearly destroyed his career: I didnt receive any new grants. February 28, 2022 Emanuela Pecchia is famously known as the wife of popular Swiss-born Italian thoracic surgeon, Paolo Macchiarini. Virginia As Selena ran from the room, Yolanda Saldivar shot her in the back. This set a dangerous example. By the time the program aired, in mid-2014, the couple were planning their marriage. A surgeon who just a decade ago was celebrated around the globe as a pioneer in stem cell transplants has been convicted of one count of causing bodily harm, a felony, in a Swedish court. Macchiarini told people that Barack and Michelle Obama, Bill and Hillary Clinton, Nicolas Sarkozy, and Vladimir Putin would attend the wedding, Andrea Bocelli would perform, and Pope Francis (a patient of his, or so he said) would officiate the ceremony, per Vanity Fair. Georgia Faced with this public relations disaster, the Karolinska Institute immediately promised to investigate the allegations but then, within days, suddenly announced that Macchiarinis contract would not be extended. So did Karolinskas dean of research. At any rate, some of his most powerful friends were themselves Nobel judges until, with his fall from grace, they fell too. The other side is flat and mobile to move air to the lungs. In April 2017, the university terminated his project. But in October 2017, the attorney general's office announced that a crime could not be proven, because the patients might have died anyway. Stem cell clinics have sprung up like weeds, offering to treat just about any ailment you can name. Paolo Macchiarinis income source is mostly from being a successful . Dr. Macchiarini received a conditional, or suspended, sentence, and was acquitted of assault charges related to two other patients who had also received the artificial organs from him at the Swedish facility. https://www.nytimes.com/2021/04/06/health/trachea-transplant-genden.html. That was a very smart idea to help maintain the fragile blood supply of the airway by leaving the esophagus in place behind it, Dr. Patterson said. But on Thursday, the surgeon, Dr. Paolo Macchiarini, was found criminally liable by a Swedish court for causing felony bodily injury to a patient he had fitted with one of the windpipes at a medical university in Sweden. Las Vegas Paolo Macchiarini: Surgeon convicted for fatal Swedish - BBC This organ was prepared without the knowledge of authorities in a veterinary lab at the University of Bristol, but no one questioned it because of its initial success. There is South Koreas Hwang Woo-suk who, in 2004, falsely claimed to have created the first human embryonic stem cells by means of cloning. But Benita stood by her man and, she said, tried to help him through a tough time. Pennsylvania With his methods still under fire in the West, he continues to work in Russia. Paolo was a world-renowned surgeon who spoke six languages, mingled with the global elite, and resembled George Clooney. Cardiothoracic surgeon Matthias Corbascio, one of Macchiarinis former colleagues at KI who first raised questions about the work, describes it as terrible and insane. The court basically gave him a slap on the wrist, says Corbascio, who is now at the University of Copenhagen. Macchiarini, meanwhile, said he did not accept the findings of the disciplinary board. She received another implant at the University College Hospital in London in 2011, after which she was able to be discharged. Yet, for the vast majority of such treatments, there is little solid evidence that they work. Emanuela Pecchia Everything We Know On Paolo Macchiarini According to Pierre Delaere, a professor of respiratory surgery at KU Leuven, Belgium, Macchiarinis experiments were bound to end badly. He was born in Basel, Switzerland to Italian parents. The idea is that scientific progress is driven by the genius of a few. She remained in intensive care for more than three years at Karolinska University Hospital and underwent more than 200 surgical procedures. New York Euan Ward reported from London, and Christina Anderson from Bastad, Sweden. For six years, she had endured a tube inserted in her windpipe, or trachea, to keep her alive, but her discomfort and distress were becoming more and more unbearable. TikToker Says Her Celebrity Surgeon Ex Conned Her Out of $50K This went on for three years until, just recently, Grinnemo was cleared of all wrongdoing. An alarmingly wide gap has grown between what we expect from stem cells and what they deliver. Powered by WordPress.com VIP. But that day is always postponed. The pope, the palace, the world leaders, the famous tenor they were all fantasies. I Googled trachea transplant and Dr. Genden popped up. Nor did they impress the institutes ethics council when Delaere lodged a formal complaint. The Italian surgeon and his Italian wife Emanuela Pecchia have one son and one daughter. Change). Countless news stories declared it a medical breakthrough. And it needs a blood supply to connect to the patients vascular system. According to hospital staff, she had roughly 40 near-death experiences during this time, the judgment said. The Karolinska Institute, alleging scientific misconduct, dismissed Dr. Macchiarini, who has long denied wrongdoing. Even the jewelry he had given her was fake. They planned to marry in the Catholic Church in Italy. Besides which, compassionate concerns dont override the basic principles of patient safety and informed consent. Although all three patients eventually died, Dr. Macchiarini was not directly accused of killing them. And in 2014, four Karolinska University Hospital doctors filed two separate reports claiming that Macchiarinis scientific papers described exaggerated the positive results of the operations and incorrectly describe[d] the postoperative status of the patients and the functionality of the implant, the timeline says. If we've learned anything from the COVID-19 pandemic, it's that we cannot wait for a crisis to respond. I dont want to live like this, she concluded. Watch He Lied About Everything on ID GO now! Fill in your details below or click an icon to log in: You are commenting using your WordPress.com account. Macchiarini, they claimed, wasnt really doing clinical research. Paolo Macchiarini